Research

CARIS tumor molecular profiling for right-in-time clinical trials | Dr. Warnick

Patients with brain tumors will undergo a genomic molecular profile evaluation for precision medicine. This study hopes to improve the lives of patients suffering from brain cancer by matching a patient's specific tumor biomarkers with targeted therapy trials. If matched, patients are rapidly enrolled and begin treatment within weeks under the care of their local doctors — eliminating stress of traveling to access clinical trials in other cities.

GammaTile v SRS newly diagnosed metastasis | Drs. DiNapoli and Gozal

This study has the goal of understanding outcomes in patients receiving Gamma Tiles vs Stereotactic Radiation Therapy for the treatment of newly diagnosed brain metastasis (cancer that has spread to the brain from another part of body).

For more information visit RoadsStudy.com >

GammaTile, STaRT observational study in neoplasms | Drs. DiNapoli and Gozal

A longitudinal observational study designed to understand long term outcomes in patients who receive Gamma Tile therapy.

Decreasing incidence of adjacent segment disease with physical therapy of the multifidus muscles after surgery | Dr. Bohinski, Physical Therapy

This study hopes to understand how increasing the strength of the innermost layer of muscle, called the multifidus, in the back can prevent future spine surgery due to adjacent level disease. Ultrasound will be used to measure the muscle cross section throughout an 8-week physical therapy program.

M6-C artificial disc versus anterior cervical discectomy and fusion | Dr. Krueger

This study compares a novel artificial cervical disc device, called Spinal Kinetics M6-C, to anterior cervical discectomy and fusion (ACDF). This study aims to understand if the M6-C artificial disc is better, worse, or the same as ACDF for pain relief and long-term outcomes. The unique design of M6-C has a compressible viscoelastic nuclear core and an annular structure. Artificial disc surgery preserves motion of the neck, whereas fusion stops motion.

TLIF with InFuse bone graft for degenerative spine | Dr. Bohinski

Evaluating the use of Infuse™ Bone Graft material in Transforaminal Lumbar Interbody Fusion (TLIF). A TLIF is a type of surgery that fuses – or joins – bones of the spine through a posterior approach. It is used to treat painful degenerative conditions of the lumbar spine. This study will determine if Infuse bone biologics are better, worse, or the same as the current standard of care (bone allograft).

Spinal cord stimulation for restless legs syndrome | Dr. Orlando

This study hopes to understand whether spinal cord stimulation can improve the lives of patients suffering from restless legs syndrome through the use of spinal cord stimulation.

Palarum sensor socks measure gait and balance to quantify functional improvement with spinal cord stimulation | Drs. Orlando and Iding

Palarum sensor socks measure gait and balance to quantify functional improvement with spinal cord stimulation (SCS). This study aims to understand the correlation between gait and spinal cord stimulation success in patients suffering from chronic back pain.

CREST-2: Carotid Revascularization and medical management for carotid stenosis| Dr. Ringer

CREST-2: Carotid Revascularization and Medical Management for Carotid Stenosis. This study compares three methods of stroke prevention: 1) intensive medical management alone compared to 2) intensive medical management in combination with a procedure to remove the plaque in your carotid artery, either surgical carotid endarterectomy, or 3) endovascular carotid angioplasty and stenting.

Post-market study long-term safety of LVIS device | Dr. Ringer

The study is a multi-center data collection of aneurysm patients treated with the LVIS device with up to 5 years follow-up. The MicroVention LVIS EVO is a braided self-expanding stent that is placed inside the parent artery to bridge across wide-neck aneurysms. The stent holds aneurysm coils in place during embolization.

Chiari Surgical Success Scale trial | Dr. Gozal

The Chiari Surgical Success Scale is a prospective multicenter patient registry that will combine patient data from all over the world to understand better how to treat and improve outcomes for patients suffering from Chiari malformation. A Chiari is a condition where the lower part of the brain, called the cerebellar tonsil, herniates down through the skull and into the spinal canal. This blocks the normal flow of cerebrospinal fluid (CSF) and causes pressure build-up.

William Tobler, MD | Spinal Elements

Evaluation of safety and efficacy of the Luna XD spinal fusion device. This retrospective study evaluated patient data to understand the safety and efficacy of the LUNA expandable interbody device for minimally invasive spinal procedures.